COVID-19 in a high-risk dual heart and kidney transplant recipient

Am J Transplant. 2020 Jul;20(7):1911-1915 doi: 10.1111/ajt.15936.
Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly infecting people worldwide, resulting in the infectious disease coronavirus disease 19 (COVID-19) that has been declared a pandemic. Much remains unknown about COVID-19, including its effects on solid organ transplant (SOT) recipients. Given their immunosuppressed state, SOT recipients are presumed to be at high risk of complications with viral infections such as SARS-CoV-2. Limited case reports in single SOT recipients, however, have not suggested a particularly severe course in this population. In this report, we present a dual-organ (heart/kidney) transplant recipient who was found to have COVID-19 and, despite the presence of a number of risk factors for poor outcomes, had a relatively mild clinical course.

Metadata
Publication type: Case Reports
Organ: Kidney; Heart
Language: English
Country: USA
MeSH terms: Adenosine Monophosphate; Adult; Alanine; Betacoronavirus; COVID-19; Cardiomyopathy, Dilated; Coronavirus Infections; Heart Transplantation; Humans; Hydroxychloroquine; Immunocompromised Host; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Male; Pandemics; Pneumonia, Viral; Radiography, Thoracic; Randomized Controlled Trials as Topic; Risk Factors; SARS-CoV-2; Treatment Outcome; 0 (Immunosuppressive Agents); 3QKI37EEHE (Remdesivir); 415SHH325A (Adenosine Monophosphate); 4QWG6N8QKH (Hydroxychloroquine); OF5P57N2ZX (Alanine); Covid-19